Good truck with some minor electrical issues. Overall, very pleased.
I purchased the 2016 F150 new and am currently at ~110k miles with no major issues or having the truck leave me anywhere. The engine V6 turbo really moves, and I've had no issues hauling heavy loads (e.g., very large wood chipper). The driver and passenger seats could be a little more comfortable for long drives, but they are not terrible. The only minor issue I've had is electrical - both rear window motors have gone (1 in warranty, 1 outside warranty) even with very limited use, and the radio very infrequently stops working (usually on a day where there was a lot of rain, but this is inconsistent). These are minor annoyances that wouldn't stop me from purchasing another F150, because I really like the truck otherwise.